The nonprofit Womens Voices for the Earth recently. You can read her, Changing the way our government and businesses handle, The Shocking Dangers of Slime and Safe Alternatives for Your Kids, The Mollys Suds Swimsuit Care Tips: How to Stay Gorgeous All Season (And Beyond), join us in the fold by subscribing to our newsletter. Air freshening sprays often have names like Joyful Paradise and Sparkling Springs that sound invigorating and natural. It has chiral centers at carbon atom 4 and 7. Some studies have suggested it might be a growing problem for aquatic life. [2] A study on Lake Michigan detected Galaxolide in 92% of water samples, and even detected airborne concentrations of the chemical in the air above the lake. 2016. For a better experience, please enable JavaScript in your browser before proceeding. "Estrogenic activity of cosmetic components in reporter cell lines: parabens, UV screens, and musks." While the action around this legislation is a step forward, consumers remain largely on their own when it comes to finding products that dont contain galaxolide. EWG Skin Deep | What is GALAXOLIDE - Environmental Working Group Vol.40, No. This effect, observed to last over 1 to 2 days after exposure, could result in an accumulation of other toxic substances within cells, and greater levels of cell damage caused by these other substances. But at this point, scientific authorities around the globe have not concluded that its harmful if used at safe concentrations. (E)-12-musk decenone, 111879-80-2 - The Good Scents Company [1] Sun P, Casteel K, Dai H, Wehmeyer KR, Kiel B, and Federle T. (2014) Distributions of polycyclic musk fragrance in wastewater treatment plant (WWTP) effluents and sludges in the United States. However, the best way to avoid Galaxolide and other harmful fragrance ingredients is to choose products that are fragrance-free (remember unscented does not mean fragrance free). [4]Kannan K, Reiner JL, Yun SH, Perotta EE, Tao L, Johnson-Restrepo B and Rodan BD. ph:(406) 543-3747 | womensvoices@womensvoices.org | 2023 All rights reserved |, Health First: A Cleaning Products Industry Roadmap for Selecting Safer Chemicals, Beyond the Label: Health Impacts of Harmful Ingredients in Cleaning Products, EXPOSED: Ingredients in Salon Products & Salon Worker Health and Safety, Johnson and Johnsons Toxic Talc: A Timeline Toward Victory. womensvoices@womensvoices.org. It is extremely toxic to aquatic animals, which makes it all the more unnerving when we know that this chemical is ending up in our Great Lakes. Breitholtz M, Wollenberger L, Dinan L. 2003. 11, pp: 3815-3820. The vagina is self-cleaning so why do companies push hygiene products on Black women? Know Your Environment. Polycyclic musk production has increased in recent . Galaxolide is a weak agonist of estrogen receptors, much weaker than phytoestrogens people consume from their veggies and not really a concern hormone-wise. for refusing to follow New York state regulations requiring them to disclose the chemical ingredients in their products and the health risks they pose. ", In March 2003, the European Chemicals Bureau (ECB) concluded that galaxolide is not a persistent, bioaccumulative and toxic substance (PBT) according to the ECB criteria and removed galaxolide from their draft list of PBTs.[8]. 2012. The New York State Department of Health and State University of New York at Albany found galaxolide present in 97 percent of breast milk samples. Prevents cells from blocking entry of toxins in animal study. [9] The EPA's PBT Profiler also finds Galaxolide to exceed the EPA's criteria as a PBT. Although galaxolide use has been on the decline for years in Europe, use of the chemical has been steadily increasing in the United States over the past 30 years. Galaxolide is a synthetic musk, a commonly used fragrance ingredient found in household products. Suspected hormone disruptor. Thats what we do in all our formulations. I use romandolide instead which alicyclic, biodegradable and very close in odour profile. Galaxolide was first synthesized in 1965, and used in the late 1960s in some fabric softeners and detergents. For example, 96% of fish tissue samples contained Galaxolide in a study of fish living downstream from wastewater treatment plants. Galaxolide is a synthetic musk, a commonly used fragrance ingredient found in household products. Galaxolide was measured in different units for some of the studies. The use of Galaxolide has been steadily increasing in the United States over the last 30 years.[1]. EU-SCCNFP safety evaluation for HHCB in cosmetics: EU-SCHER Opinion on HHCB safety for human health. The presence of galaxolide in drinking water raises serious concerns about its health effects on humans. Galaxolide has been found in 32 of the 52 people tested in EWG/Commonweal studies. Body Odor May Smell Worse to You Than Your Ancient Ancestors ph:(406) 543-3747 | womensvoices@womensvoices.org | 2023 All rights reserved |, Health First: A Cleaning Products Industry Roadmap for Selecting Safer Chemicals, Beyond the Label: Health Impacts of Harmful Ingredients in Cleaning Products, EXPOSED: Ingredients in Salon Products & Salon Worker Health and Safety, Johnson and Johnsons Toxic Talc: A Timeline Toward Victory. Two musks that are cited in many studies as the epitome of evil are Galaxolide and Tonalide - they have been claimed to be endocrine disrupters (i.e. Emerging science indicates that humans accumulate galaxolide in every part of the body. [2], Galaxolide was discovered at IFF in the 1960s, by Heering and Beets. PO Box 8743 The Skin Deep scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern. Executive Programs. NO. In the case of galaxolide, the European Chemicals Agency (ECHA) and the United States Environmental Protection Agency (EPA) do not consider it to be a persistent, bioaccumulative or toxic chemical whats known as a PBT. [2] Based on test data, the EU Scientific Committee for Consumer Safety included galaxolide in their proposal for extending the allergen information on cosmetic products as it claims to have seen only up to 100 individual cases worldwide in the last several decades who have reported irritation or allergic reactions to galaxolide through the use of cosmetic products. 2.1 Fragrances. The greatest known concern with Galaxolide, is the cumulative impact of Galaxolide on our environment. This chemical is highly toxic to aquatic life. Until just recently the only information available about SC Johnsons use of Galaxolide came from Chemical Data Reports filed with the EPA, which are required for the six companies that use more than 25,000 pounds of Galaxolide annually in the U.S. SC Johnson was one if just six companies submitted their report, but in contrast to their industry-leading commitment to transparency, chose to designate the actual amount of Galaxolide they use as confidential. Since fragrance ingredients are not required to be disclosed on a product label or website, consumers will most often have to ask a manufacturer if their products contain Galaxolide in order to avoid the chemical. Its odor is described as a clean, sweet, floral, woody musk,[5] Research has shown that it is in particular the (4S,7R) and the (4S, 7S) forms of galaxolide that are the most powerful musk notes, with odor thresholds of 1ng/L or less. Through research, she learned about the hazards of household cleaners and detergents and decided to create a line of products that are Always Safe for People and the Planet. Many, many fine fragrances still contain Polycyclic musks. For us, ingredient selection is about integrity. Support Grows for Global Treaty Amendment to Ban Advertising, Display, Sales, and Offering of Sales of Mercury Skin Lighteners. Visit ChemicalBook To find more GALAXOLIDE(1222-05-5) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. Chemosphere 61, pp: 693700. Essentially, PBTs do not break down easily in the environment, build up over time and are highly toxic to the environment. 2008. Galaxolide - an overview | ScienceDirect Topics Womens Voices assessed galaxolide with GreenScreen, an internationally recognized tool for evaluating and comparing the hazards of chemicals. Of all artificial musks, these most resemble the primary odoriferous compound from Tonkin musk in its "large ringed" structure. A 2009 study in Austria detected galaxolide in the blood plasma of 91 percent of participants; those who used scented lotions and perfumes had significantly higher levels of galaxolide than those who did not. Most musk fragrance used in perfumery today is synthetic. Almost a quarter of cases of fragrance-associated asthma in the workplace occurred in workers who had no previous history of asthma, but developed it as a result of exposure to scented products on the job. J Toxicol Environ Health A 68(4): 239-51. This approach came up recently when SC Johnson became the subject of some Internet bullying about the fragrance ingredient galaxolide. Big Data and Analytics Program; Online Programs; Corporate Training Programs; Management Programs. Galaxolide (also called "HHCB") is a common synthetic musk whose use has been steadily increasing in the U.S over the last 30 years. 2014. These findings were further confirmed by the GreenScreen for Safer Chemicals Assessment that was commissioned by Womens Voices for the Earth in 2015 which determined Galaxolide to be a Benchmark 1 chemical (Chemical of Highest Concern) due to its persistent, bioaccumulative and toxic properties. GreenScreen for Safer Chemicals Assessmen, New report from California EPA reveals numerous toxic chemicals in nail products, Impossible Instructions: Safety Concerns with Toxic Chemicals and User Instructions in Professional Salon Products, What the Thinx Class Action Settlement Means for All of Us. Because of this negative publicity most manufactures of detergents request that their fragrances be Polycyclic free. [3], It was first synthesized in 1965 and its discovery was mainly due to the work by Beets on the osmophoric group of the polycyclic musks, where they tried to improve existing synthetic musks by making them more stable and hydrophobic [4], Galaxolide has become the key synthetic musk ingredient belonging to the polycyclic musk group as defined by the International Fragrance Association (IFRA). This can result in developmental, reproductive, metabolic, brain and behavior problems. EWG's Guide to Healthy Cleaning | GALAXOLIDE | Substance 2587-2597. The greatest known concern with Galaxolide, is the cumulative impact of Galaxolide on our environment. [5] 97% of breast milk samples tested contained Galaxolide.[6]. The use of Galaxolide has been steadily increasing in . Environmental Toxicology and Chemistry. 2003. Good question. Click here. The GreenScreen assigned Galaxolide a score of Benchmark 1. . The easiest way to stay tuned in to exciting events, breaking actions & updates on the issues you care about! There is very clear evidence that galaxolide persists for a long time in people and the environment. In addition, it is persistent in the environment due to a low rate of biodegradation (Balk 1999; Daughton 1999). and Beets M.G.J., 1965, New Tricyclic Isochromans with Musk Odour. InChI=1S/C18H26O/c1-11-9-19-10-13-7-15-16(8-14(11)13)18(5,6)12(2)17(15,3)4/h7-8,11-12H,9-10H2,1-6H3/t11?,12-/m1/s1, National Institute of Standards and (Hutter 2009) 100% of humans tested were found to have Galaxolide in their fat tissue. I think it's a personal choice. 2004. These semi-volatile compounds exhibit a long-lasting smell, having been employed as inexpensive substitutes for natural and rare musks in daily formulations [3, 5, 6]. And, its about upholding the scientific process taking the time to gather data and make thoughtful decisions. The nonprofit Womens Voices for the Earth recently released a detailed review of the hazards posed by galaxolide, underscoring its toxicity and ability to accumulate in our bodies and ecosystems. The EWG VERIFIED mark means a product meets EWGs strictest criteria for transparency and health. All chemicals have the potential to be harmful at certain levels. Galaxolide does not break down well over time, so the cumulative pollution continues to build in our waterways and soil. Average mass 258.398 Da. Monoisotopic mass 258.198364 Da. The Hidden Dangers of Galaxolide - Molly's Suds Synthetic musks are aroma compounds used worldwide as substitutes for natural musks, which have become ubiquitous pollutants in the environment. Apparently, SC Johnsons safety staff disputes the assertion that Galaxolide is a PBT. [19] Yet, studies show, it is commonly detected in rivers,[20] drinking water,[21] lake sediment[22] and fish tissue. Key Questions on Galaxolide and SC Johnson - Women's Voices for the Earth 47, pp: 4821-4825. In our report, Unpacking the Fragrance Industry, Womens Voices for the Earth raises the alarm on RIFMs safety standards. Galaxolide is the trade name from International Flavors & Fragrances Inc. (IFF) for the fragrance material with CAS Registry Number 1222-05-5 and CAS chemical name cyclopenta(g)-2-benzopyran, 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-. Unfortunately, Galaxolide is detected in our environment nearly everywhere testing has been conducted. Its melting point is -20C and its boiling point is estimated to be 330C based on a boiling point of 160C at 4hPa. Despite this discovery and the discovery of other pathways for synthesis of macrocyclic musks, compound of this class were not commercially produced and commonly utilized until the late 1990s due to difficulties in their synthesis and consequently higher price. (Natural musks haven't been used in years since they have to be harvested from the glands of male musk deer.) Galaxolide is identi!ed by the CAS # 1222-05-5 and is also known by the synonyms: 1,3,4,7,8-hexahdro- 4,6,6,7,8,8,-hexamethyl- cyclopenta[g[-benzopyran (HHCB) and its INCI name, hexamethylindanopyran. Environmental Science and Technology. In the case of galaxolide, weve stayed on top of the research, and were pleased when some recent studies showed alternatives for galaxolide that meet our high standards. Galaxolide. [6], Galaxolide has a measured bioconcentration factor (BCF) in fish in a range of 600-1600 and a log octanol-water partition coefficient (Log Kow) of around 5.5 (5.3 5.9). But not at such a high cost to our health and the environment. Environmental Science and Technology. All Rights Reserved. United Kingdom Patent: 991,146. Everyone deserves to live in a healthy and safe environment. to which I answer that they are not, with a few little details here and there to try to make them understand - but it's no matter, a lot of the time, the moment I say "no" to their question, they are looking at me like I am a criminal. A coalition of 42 public interest groups applauded the state Department of Environmental Conservations effort. The safest products score well by both measures, with a low hazard rating and . (2009) Occurrence of Pharmaceuticals and Personal Care Products in Fish: Results of a National Pilot Study in the United States. Tools Galaxolide (trade name; also known as Abbalide, Pearlide, Astrolide, Musk 50, Polarlide; chemical name 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8,-hexamethyl-cyclopenta [ g ]benzopyran or HHCB, hexamethylindanopyran) is a synthetic musk with a clean sweet musky floral woody odor used in fragrances. I love fish and worms. Incense and fragrant oils were used as far back as 3100 B.C. GreenScreen for Safer Chemicals is an internationally recognized tool for comparing and assessing the hazards of chemicals in order to identify those of high concern and evaluate safer alternatives. Scientists have found it in several of the Great Lakes including Lake Erie, Lake Ontario, Lake Michigan as well as in Great Lakes . These reports must also describe any company research on the health and environmental effects of their cleaning product ingredients. In 2009, Earthjustice took Procter & Gamble, Colgate-Palmolive and other household cleaner manufacturing giants to court for refusing to follow New York state regulations requiring them to disclose the chemical ingredients in their products and the health risks they pose. Womens Voices for the Earth commissioned a GreenScreen for Safer Chemicals assessment of Galaxolide to determine its hazard level. Galaxolide Provides an Example of How SC Johnson Makes Ingredient On December 20, 2019, EPA finalized the designation of 20 chemical substances as a high-priority for risk evaluation under TSCA, Galaxolide is one of these high-priority chemicals being evaluated for risk. We let science steer our way. People have been eagerly filling their homes with beautiful aromas for thousands of years. There is very clear evidence that galaxolide persists for a long time in people and the environment. Science of the Total Environment. OSPAR review of various musk ingredients: EU Scientific Committee on Health and Environmental Risks; Environmental Assessment of HHCB, ToxServices (2015) 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta--2-benzopyran (HHCB) (CAS# 1222-05-5) GreenScreen for Safer Chemicals (GreenScreen) Assessment. The safest products score well by both measures, with a low hazard rating and a fair or better data availability rating. 2023 by the U.S. Secretary of Commerce . [11] The case study highlights the fact that synthetic musks (such as Galaxolide) were flagged as PBTs. Data from NIST Standard Reference Database 69: NIST Chemistry WebBook; When household products containing Galaxolide are used, the long-lasting fragrance chemical ends up in wastewater, which survives wastewater treatment plants to end up in our waterways and eventually in the Great Lakes. PubMed online scientific bibliography data. Science of the Total Environment. Based on this data SC Johnson determined that synthetic musks like Galaxolide were not persistent, and therefore not classified as PBTs. Manufacturers still using Galaxolide simply must follow this lead. Specifically, the GreenScreen assigned the Benchmark 1 score due to Galaxolides high persistent, bioaccumulative and aquatic toxicity properties. 2009 November 1; 135(11): 1192. Galaxolide: A Long-lasting Fragrance Contaminating the Great Lakes They found it does not accumulate and remains at levels that have been shown to be safe for human health and the environment. [3] Another study detected Galaxolide in 83% of Atlantic salmon sampled. Standard Reference Data Act. Thats how we make choices we can feel good about, and you can too. Learn about SC Johnson's efforts to end malaria. Polymerised Galaxolide | Basenotes SC Johnson identifies the presence of Galaxolide in their products by using the synonym hexamethylindanopyran. (2009) Synthetic musks in blood of healthy young adults: Relationship to cosmetics use. [9]US Environmental Protection Agency (2014) TSCA Work Plan Chemical Risk Assessment, HHCB, 1,3,4,6,7,8-Hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-g-2-benzopyran CASRN: 1222-05-5. Print and share this flyer to help start a conversation about fragrance safety and health impacts with neighbors, co-workers, etc. Unfortunately it's also several times more expensive . The land-based input and partition behavior of synthetic musks in sediments and seawater are important for understanding . Galaxolide: A Threat to the Environment and Human Health Its about understanding ingredients safety margins and adhering to them conservatively and faithfully. Now that we have the data to support it, were going in what appears to be an even better direction. The research team was able to identify. [1] 100% of drinking water samples from a water treatment plant contained Galaxolide. With any ingredient, its important to know how much can be used safely, and stay below that safe level. Rimkus, G.G. 12, pp. US Email: Fred Keifer. Polycyclic musk production has increased in recent years due to a decrease in production of nitromusks secondary to concerns about toxicological effects (Daughton 1999). Galaxolide (HHCB) and tonalide (AHTN) are polycyclic musk compounds (PMCs) . It was discovered accidentally as a result of Baur's attempts at producing a more effective form of trinitrotoluene (TNT). Galaxolide: Toxic? Alternatives? | Basenotes found that galaxolide levels in the lake sediment are doubling every eight to 16 years. Database and to verify that the data contained therein have [7][8] However, the EPA's assessment of galaxolide found it to be moderately persistent and bioaccumulative and highly toxic to aquatic organisms. To create natural scents in household cleaning products, manufacturers often rely on the synthetic chemical, galaxolide. Galaxolide | C18H26O | CID 91497 - PubChem Go To: Top. Copyright 2021 Molly's Suds. Number 1. 38, No.2, pp. PO Box 8743 (Natural musks havent been used in years since they have to be harvested from the glands of male musk deer.) Whats new is not necessarily always better. [3] Alicyclic musks are dramatically different in structure than previous musks (aromatic, polycyclic, macrocyclic) in that they are modified alkyl esters. Find personal care, cleaning, and food products on the EWG Healthy Living app. Synthetic musks are a class of synthetic aroma compounds to emulate the scent of deer musk and other animal musks (castoreum and civet). Beets in 1957. at the Posner Center Because the EPA often does not adequately test the chemicals sold on the U.S. market, Womens Voices for the Earth and Michigan Clean Water Action shouldered the responsibility of reviewing galaxolide. Galaxolide | C18H26O | CID 91497 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety . Galaxolide and tonalide modulate neuroendocrine activity in marine Galaxolide (42 products available) View by: List | Grid || Supplier Location Near Me All India Liquid Galaxolide Chemical, Packaging Size: 50 kg 600/ KG Get Latest Price Grade Standard: Technical Grade Packaging Size: 50 kg Packaging Type: Drum Physical State: Liquid Boiling Point: 160 DegreeC Molecular Formula: C18H26O read more. Products containing galaxolide drain into wastewater, pass easily through water treatment plants, and, eventually, spill into waterways like the Great Lakes. GALAXOLIDE | 1222-05-5 - ChemicalBook 2009. Support Grows for Global Treaty Amendment to Ban Advertising, Display, Sales, and Offering of Sales of Mercury Skin Lighteners. We are committed to working for justice and equity, and are in solidarity with social, racial, and environmental justice organizations to build community, understanding and honest dialogue to address the root causes of violence, harm and hate. Find out. Synthetic fragrance in cosmetics, cleaning agents, detergents, air fresheners, perfumes. A GreenScreen takes into account data on 18 different health and environmental endpoints to determine a hazard score. Available: https://www.epa.gov/sites/production/files/2015-05/documents/scjohnson-study-2002.pdf. August 2014. Other structurally different but functionally similar compounds also came to be known as musks. galaxolide substitute The smell in the process is terribly urinous. Furthermore, as a sustainability leader in the household products industry, a decision by SC Johnson to eliminate Galaxolide would make a tremendous statement, and would without a doubt impact those other five companies in the industry still using Galaxolide in their products. The vagina is self-cleaning so why do companies push hygiene products on Black women? Galaxolide has also been found to inhibit the larval development of different species of small aquatic crustaceans, called copepods, at low levels (Breitholtz 2003; Wollenberger 2003), indicating that it is highly toxic to some aquatic organisms. Largely, these studies have never been published or peer-reviewed, and are not publicly available. Learn more. So where is SCJ at with their progress? DOWNLOAD and viewthe complete GreenScreen assessment of Galaxolide. 41, No. You can read her whole story here. One study found Galaxolide in 81% of water samples from Great Lakes tributaries that run through urban areas. Be sure to check out our DIY page for natural alternatives to many household cleaners we update it often! PBT stands for persistent, bioaccumulative and toxic chemicals. The Skin Deep ingredient hazard score, from 1 to 10, reflects known and suspected hazards linked to the ingredients. Vol. Galaxolide - Abbalide Latest Price, Manufacturers & Suppliers The presence of galaxolide in drinking water raises serious concerns about its health effects on humans. But, behind those pristine labels, youll find a combination of mild irritants to downright toxic chemical ingredients. Muscone and civetone are macrocyclic ketones. Galaxolide is by far the most common of the polycyclic musks, and production and use of this compound has increased as production and use of nitromusks decreases.
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